elispot Concept

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Overview

research area of

• Awino, Elias, Research Officer, ILRI, ILRI
• Pelle, Roger, Principal Scientist - Molecular Parasitologist, ILRI, ILRI
• Saya, Rosemary, Research Officer, ILRI, ILRI
• Steinaa, Lucilla, Principal Scientist - Cellular Immunologist, ILRI, ILRI
• Svitek, Nicholas, Senior Scientist - Cellular Immunologist, ILRI, ILRI

subject area of

• An Ad/MVA vectored Theileria parva antigen induces schizont-specific CD8+ central memory T cells and confers partial protection against a lethal challenge.
• Analysis of the Cellular Immune Responses to Vaccines
• Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen.
• Differential T‐cell responses to a chimeric Plasmodium falciparum antigen; UB05‐09, correlates with acquired immunity to malaria
• Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle.
• TpUB05, a Homologue of the Immunodominant Plasmodium falciparum Protein UB05, Is a Marker of Protective Immune Responses in Cattle Experimentally Vaccinated against East Coast Fever.