selected publications
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article
- CD8 T-cell responses against the immunodominant Theileria parva peptide Tp249-59 are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes.. Immunology. 149:172-185. 2016
- Analysis of the Cellular Immune Responses to Vaccines. Methods of Molecular Biology. 1349:247-262. 2016
- Enabling the Development and Deployment of Next Generation Point-of-Care Diagnostics. PLOS Neglected Tropical Diseases. 9. 2015
- Exploring farmer preferences for contagious bovine pleuropneumonia vaccination: a case study of Narok District of Kenya.. Preventive Veterinary Medicine. 110:356-369. 2013
- Extensive Polymorphism and Evidence of Immune Selection in a Highly Dominant Antigen Recognized by Bovine CD8 T Cells Specific for Theileria annulata. Infection and Immunity. 79:2059-2069. 2011
- Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity.. PLOS ONE. 6. 2011
- Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses.. Veterinary Immunology and Immunopathology. 140:244-251. 2011
- CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity.. European Journal of Immunology. 39:2459-2469. 2009
- Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8⁺ T cell responses. Veterinary Immunology and Immunopathology. 130:107-113. 2009
- Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva. Veterinary Immunology and Immunopathology. 128:269. 2009
- The bovine CD8+ T-cell response to Theileria parva displays epitope immunodominance and oligoclonality. Veterinary Immunology and Immunopathology. 128:288. 2009
- Enhanced discrimination of African swine fever virus isolates through nucleotide sequencing of the p54, p72, and pB602L (CVR) genes. Virus Genes. 38:85-95. 2009
- Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function.. International Journal for Parasitology. 38:1693-1704. 2008
- Assessment of in vitro interferon-γ responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type. Veterinary Immunology and Immunopathology. 124:192-197. 2008
- Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle.. Veterinary Immunology and Immunopathology. 121:216-221. 2008
- Characterization of the Fine Specificity of Bovine CD8 T-Cell Responses to Defined Antigens from the Protozoan Parasite Theileria parva. Infection and Immunity. 76:685-694. 2008
- Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva.. Veterinary Immunology and Immunopathology. 115:383-389. 2007
- A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology.. Immunome Research. 3:2-2. 2007
- Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus.. Vaccine. 25:1287-1296. 2007
- Extensive Genotypic Diversity in a Recombining Population of the Apicomplexan Parasite Theileria parva. Infection and Immunity. 74:5456-5464. 2006
- Post-translational signal peptide cleavage controls differential epitope recognition in the QP-rich domain of recombinant Theileria parva PIM.. Molecular and Biochemical Parasitology. 149:144-154. 2006
- Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 103:3286-3291. 2006
- Using the transcriptome to annotate the genome revisited: application of massively parallel signature sequencing (MPSS).. Gene. 366:104-108. 2006
- Longitudinal study of ECF dynamics in Narok district in Kenya 2006
- Antibodies against bovine herpesvirus 4 are highly prevalent in wild African buffaloes throughout eastern and southern Africa.. Veterinary Microbiology. 110:209-220. 2005
- Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes.. Science. 309:134-137. 2005
- Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage. Nucleic Acids Research. 33:5503-5511. 2005
- Antigens for an east coast fever vaccine 2004
- East coast fever vaccine based on ctl-specific schizont antigens 2004
- Heterologous priming-boosting immunization of cattle with Mycobacterium tuberculosis 85A induces antigen-specific T-cell responses.. Infection and Immunity. 71:6906-6914. 2003
- Genomics of Theileria parva 2002
- Transcription of the unique ruminant class II major histocompatibility complex-DYA and DIB genes in dendritic cells.. European Journal of Immunology. 31:82-86. 2001
- A highly sensitive, non-radioactive assay for T cell activation in cattle: applications in screening for antigens recognised by CD4(+) and CD8(+) T cells. Journal of Immunological Methods. 239:85-93. 2000
- Cloning, sequence and mRNA expression of bovine interleukin-16.. Dna Sequence. 10:425-428. 2000
- Protective Immune Mechanisms against Theileria parva: Evolution of Vaccine Development Strategies. Parasitology Today. 15:263-267. 1999
- Bovine γδ T-Cell Responses to the Intracellular Protozoan Parasite Theileria parva. Infection and Immunity. 67:2241-2249. 1999
- Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection. Vaccine. 16:1276-1282. 1998
- Immunization of Cattle by Infection with Cowdria ruminantium Elicits T Lymphocytes That Recognize Autologous, Infected Endothelial Cells and Monocytes†. Infection and Immunity. 66:1855-1860. 1998
- Immunisation with live attenuated Salmonella dublin expressing a sporozoite protein confers partial protection against Theileria parva. Vaccine. 16:834-841. 1998
- Distinct CD4+ T cell helper requirements in Theileria parva-immune and -naive bovine CTL precursors.. Journal of Immunology. 159:4539-4545. 1997
- Distinct CD4(+) T cell helper requirements in Theileria parva-immune and -naive bovine CTL precursors. Journal of Immunology. 159:4539-4545. 1997
- Parasite strain specificity of bovine cytotoxic T cell responses to Theileria parva is determined primarily by immunodominance.. Journal of Immunology. 155:4854-4860. 1995
- Contribution of T-cell responses to immunity and pathogenesis in infections with Theileria parva 1995
- PARASITE STRAIN SPECIFICITY OF BOVINE CYTOTOXIC T-CELL RESPONSES TO THEILERIA-PARVA IS DETERMINED PRIMARILY BY IMMUNODOMINANCE. Journal of Immunology. 155:4854-4860. 1995
- Parasite strain specificity of precursor cytotoxic T cells in individual animals correlates with cross-protection in cattle challenged with Theileria parva 1995
- Adoptive transfer of immunity to Theileria parva in the CD8+ fraction of responding effluent lymph 1994
- Standardization of a technique for analysing the frequency of parasite-specific cytotoxic T lymphocyte precursors in cattle immunized with Theileria parva 1992
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document
- Cross-disciplinary and participatory livestock and human health research for successful control of zoonoses in the developing world 2008
- Distinct CD4 + T cell helper requirements in Theileria parva-immune and -naive bovine CTL precursors 1997
- Theileriosis: progress towards vaccine development through understanding immune responses to the parasite 1995
- Effect of timing and intensity of challenge following immunization against East Coast fever 1987
- Immunization against east coast fever: The use of selected stocks of Theileria parva for immunization of cattle exposed to field challenge 1987
- Effect of chronic trypanosomiasis on immunization against east coast fever 1986