antibody Concept

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research area of

• Awino, Elias, Research Officer, ILRI, ILRI
• Fevre, Eric, Joint Appointee - Principal Scientist, Epidemiologist, ILRI, ILRI
• Kumari, Safaa, Head of ICARDA Seed Health Laboratory/Plant Virologist, ICARDA, ICARDA
• Nene, Vish, Co-Leader, Animal and Human Health, ILRI, ILRI
• Okoth, Edward, Epidemiologist/Field Team Coordinator & Institutional Veterinarian, ILRI, ILRI
• Pelle, Roger, Principal Scientist - Molecular Parasitologist, ILRI, ILRI
• Poole, Jane, Consultant, ILRI, ICRAF
• Rahman, Habibur, Fisheries Development Officer, WORLDFISH, ILRI
• Rekik, Mourad, Principal Scientist - Small Ruminant Physiology and management, ICARDA, ICARDA
• Schieck, Elise, Scientist - Mycoplasma, ILRI, ILRI
• Steinaa, Lucilla, Principal Scientist - Cellular Immunologist, ILRI, ILRI
• Taylor, Katarlah, Manager, Events, IFPRI, IFPRI

subject area of

• A longitudinal survey of African swine fever in Uganda reveals high apparent disease incidence rates in domestic pigs, but absence of detectable persistent virus infections in blood and serum.
• A minor role of CD4+ T lymphocytes in the control of a primary infection of cattle with Mycoplasma mycoides subsp. mycoides.
• A subset of Cowdria ruminantium genes important for immune recognition and protection.
• An Improved Antiserum for Sensitive Serologic Detection of Chickpea chlorotic dwarf virus
• Analysis of the Cellular Immune Responses to Vaccines
• Analysis of the immunoproteome of Mycoplasma mycoides subsp. mycoides small colony type reveals immunogenic homologues to other known virulence traits in related Mycoplasma species.
• Antibodies against bovine herpesvirus 4 are highly prevalent in wild African buffaloes throughout eastern and southern Africa.
• Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro.
• Approaches to vaccination against Theileria parva and Theileria annulata.
• B-1-like cells exist in sheep. Characterization of their phenotype and behaviour.
• BIOCHEMICAL ANALYSIS OF PRELIMINARY CLUSTERS IN THE NON-LINEAGE PANEL
• Baseline analysis of Mycoplasma mycoides subsp. mycoides antigens as targets for a DIVA assay for use with a subunit vaccine for contagious bovine pleuropneumonia
• Bluetongue and epizootic haemorrhagic disease virus in local breeds of cattle in Kenya.
• Bovine trypanotolerance: A natural ability to prevent severe anaemia and haemophagocytic syndrome?
• CD5+ B lymphocytes are the main source of antibodies reactive with non‐parasite antigens in Trypanosoma congolense‐infected cattle
• Camelid nanobodies with high affinity for broad bean mottle virus: a possible promising tool to immunomodulate plant resistance against viruses
• Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides fail to generate neutralizing antibodies and succumb to disease on challenge
• Characterisation of bovine transferrin receptor on normal activated and Theileria parva-transformed lymphocytes by a new monoclonal antibody.
• Characterization of Monoclonal Antibodies to the αIIbβ3 Integrin on Bovine Platelets
• Cloning, Characterization, and Expression of a 200-Kilodalton Diagnostic Antigen of Babesia bigemina
• Comparative analysis of adaptive immune responses following experimental infections of cattle with bovine viral diarrhoea virus-1 and an Asiatic atypical ruminant pestivirus.
• Comparative evaluation of fluorescence polarization assay and competitive ELISA for the diagnosis of bovine brucellosis vis-a-vis sero-monitoring.
• Comparative evaluation of novel African swine fever virus (ASF) antibody detection techniques derived from specific ASF viral genotypes with the OIE internationally prescribed serological tests.
• Comparison of TAS-ELISA, dot and tissue blot, ISEM and immunocapture RT-PCR assays for the detection of Yam mosaic virus in yam tissues
• Conformationally Restricted Peptides from Rice Proteins Elicit Antibodies That Recognize the Corresponding Native Protein in ELISA Assays
• Delivery of the Theileria parva p67 antigen to cattle using recombinant vaccinia virus: IL-2 enhances protection
• Delivery of the p67 Sporozoite Antigen of Theileria parva by Using Recombinant Salmonella dublin: Secretion of the Product Enhances Specific Antibody Responses in Cattle
• Development of a Novel Cocktail Enzyme-Linked Immunosorbent Assay and a Field-Applicable Lateral-Flow Rapid Test for Diagnosis of Contagious Bovine Pleuropneumonia.
• Development of serological procedures for rapid, sensitive and reliable detection of yam mosaic virus in yam tissues
• Effective in vivo depletion of T cell subpopulations and loss of memory cells in cattle using mouse monoclonal antibodies
• Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection.
• Evaluation of an ELISA for detection of antibodies to Babesia bovis in cattle in Australia and Zimbabwe.
• Evaluation of antigen detection and antibody detection tests for Trypanosoma evansi infections of buffaloes in Indonesia.
• Evaluation of the immune responses against reduced doses of Brucella abortus S19 (calfhood) vaccine in water buffaloes (Bubalus bubalis), India.
• Expression and characterization of Ov-47, a dominant antigen of Onchocerca volvulus.
• Expression of RoTat 1.2 cross-reactive variable antigen type in Trypanosoma evansi and T. equiperdum
• First Report of the Occurrence of Trichinella-Specific Antibodies in Domestic Pigs in Central and Eastern Uganda.
• Fluorescence polarization assay: Diagnostic evaluation for porcine brucellosis
• Global Foot-and-Mouth Disease Research Update and Gap Analysis: 6 - Immunology.
• High antibody titres against predicted Mycoplasma surface proteins do not prevent sequestration in infected lung tissue in the course of experimental contagious bovine pleuropneumonia
• Identification of a synthetic peptide inducing cross-reactive antibodies binding to Rhipicephalus (Boophilus) decoloratus, Rhipicephalus (Boophilus) microplus, Hyalomma anatolicum anatolicum and Rhipicephalus appendiculatus BM86 homologues.
• Identification of mechanisms of natural resistance to African trypanosomiasis in cattle.
• Identification of targets of monoclonal antibodies that inhibit adhesion and growth in Mycoplasma mycoides subspecies mycoides.
• IgG antibodies from dourine infected horses identify a distinctive Trypanosoma equiperdum antigenic pattern of low molecular weight molecules.
• Immune response of cattle infected with african trypanosomes
• Immune responses of cattle to African trypanosomes: protective or pathogenic?
• Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: targetting the disease rather than the parasite
• Immunological Characterization and Expression in Escherichia coli and Baculovirus Systems of a Trypanosoma vivax Antigen Detected in the Blood of Infected Animals
• Lentiviral arthritis and encephalitis in goats in north-west Syria.
• Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralizing epitopes: implications for a vaccine.
• Molecular characterisation of a Theileria lestoquardi gene encoding a candidate sporozoite vaccine antigen.
• Molecular evolution of a central region containing B cell epitopes in the gene encoding the p67 sporozoite antigen within a field population of Theileria parva
• Monoclonal antibodies identify two neutralization-sensitive epitopes in Besnoitia besnoiti endocytes.
• Naturally acquired Rift Valley fever virus neutralizing antibodies predominantly target the Gn glycoprotein
• Neutralization of bovine Concanavalin‐A T cell supernatant‐mediated anti‐Cowdria ruminantium activity with antibodies specific to Interferon gamma but not to tumor necrosis factor
• Nomenclature and characterization of leukocyte differentiation antigens in ruminants.
• Novel baculovirus-derived p67 subunit vaccines efficacious against East Coast fever in cattle
• Performance evaluation of five commercial assays in assessing seroprevalence of HEV antibodies among blood donors
• Plasmodium falciparum variant erythrocyte surface antigens: a pilot study of antibody acquisition in recurrent natural infections.
• Polyclonal Antibodies to the Bacterially Expressed Coat Protein of Faba Bean Necrotic Yellows Virus
• Presence of antibodies against tick-borne encephalitis virus in sheep in Tunisia, North Africa.
• Prevalence of antibodies against respiratory viruses (parainfluenza virus type 3, respiratory syncytial virus, reovirus and adenovirus) in relation to productivity in Syrian Awassi sheep
• Production and characterization of monoclonal antibodies for aflatoxin B1.
• Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites.
• Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice.
• Rapid latex agglutination (RLA) test for the diagnosis of Babesia Argentina
• Recombinant Antigen Targets for Serodiagnosis of African Swine Fever
• Recombinant Newcastle disease virus expressing African swine fever virus protein 72 is safe and immunogenic in mice.
• Recombinant RoTat 1.2 variable surface glycoprotein as antigen for diagnosis of Trypanosoma evansi in dromedary camels.
• Sensitivity and specificity of antigen-capture ELISAs for diagnosis of Trypanosoma congolense and Trypanosoma vivax infections in cattle.
• Seroepidemiological Study of Interepidemic Rift Valley Fever Virus Infection Among Persons with Intense Ruminant Exposure in Madagascar and Kenya
• Serological Evidence of MERS-CoV Antibodies in Dromedary Camels (Camelus dromedaries) in Laikipia County, Kenya
• Serological and molecular evidence of Brucella species in the rapidly growing pig sector in Kenya.
• Serological evidence of Francisella tularensis in febrile patients seeking treatment at remote hospitals, Northeastern Kenya, 2014-2015
• Serological testing of cattle experimentally infected with Mycoplasma mycoides subsp. mycoides Small Colony using four different tests reveals a variety of seroconversion patterns
• Seroprevalence of anti‐Mycobacterium avium subsp. paratuberculosis antibodies in female sheep in Tunisia
• Studies on a Nigerian isolate of banana streak badnavirus: I. Purification and enzyme linked immunosorbent assay
• Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge
• Surface Ig on B lymphocytes from cattle and sheep.
• Susceptibility of TNF-α-deficient mice to Trypanosoma congolense is not due to a defective antibody response
• The effects of aflatoxin exposure on Hepatitis B-vaccine induced immunity in Kenyan children.
• The persistence of Theileria parva infection in cattle immunized using two stocks which differ in their ability to induce a carrier state: analysis using a novel blood spot PCR assay
• The role of anti-variable surface glycoprotein antibody responses in bovine trypanotolerance.
• TpUB05, a Homologue of the Immunodominant Plasmodium falciparum Protein UB05, Is a Marker of Protective Immune Responses in Cattle Experimentally Vaccinated against East Coast Fever.
• Trypanosoma congolense:B-Lymphocyte Responses Differ between Trypanotolerant and Trypanosusceptible Cattle
• Trypanosome non-specific IgM antibodies detected in serum of Trypanosoma congolense-infected cattle are polyreactive.
• Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus.
• Vaccines against Theileria parva.