Integrated Management of Aflatoxin Contamination: Progress towards Enhancing Food and Feed Quality and Human and Animal Health uri icon


  • Aflatoxins are the secondary metabolites produced by Aspergillus flavus and A. parasiticus inseveral crops and commodities. They are carcinogenic, teratogenic and immunosuppressantsthat are implicated in growth retardation in children, immune-suppression, interference inmicronutrient metabolism, liver cirrhosis, liver and esophageal cancers and decreased humanand animal productivity1,2 (Figure 1). Acute severe intoxication of aflatoxin can result indeath3. Research in Asia and Sub-Saharan Africa (SSA) has shown that aflatoxincontamination is widespread in staple crops like groundnut, maize, millet, chillies, sorghum,etc., and even in milk from animals fed with contaminated feed2. In the developed countries,aflatoxins are regulated through good production and post-harvest practices and stringentfood safety monitoring. However, application of such strategies in the developing countriesare difficult due to differences in production practices, food insufficiency, lack of resourcesand technology for monitoring and

publication date

  • 2007