Publications in VIVO

Co-author Network

Nene, Vish Co-Leader, Animal and Human Health, ILRI

ILRI

Kenya

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article
- Synergistic Effect of Two Nanotechnologies Enhances the Protective Capacity of the Theileria parva Sporozoite p67C Antigen in Cattle. Journal of Immunology. 206:686-699. 2021
- Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional intra-specific genetic diversity.. PLOS Neglected Tropical Diseases. 14. 2020
- African Vaccinology Network (AfVANET): an African network by African scientists. PAN AFRICAN MEDICAL JOURNAL. 37:66-66. 2020
- Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo- derived strain and reveals exceptional intra-specific genetic diversity. bioRxiv. 2020
- Re-annotation of the Theileria parva genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved pathway in many organisms.. BMC Genomics. 21:279. 2020
- Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation. Scientific Reports. 10:3982. 2020
- A randomised vaccine field trial in Kenya demonstrates protection against wildebeest-associated malignant catarrhal fever in cattle.. Vaccine. 37:5946-5953. 2019
- Vaccination against CCPP in East Africa.. Veterinary Record. 185:272-272. 2019
- Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever.. International Journal for Parasitology-Drugs and Drug Resistance. 9:80-86. 2019
- Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle.. BMC Veterinary Research. 15:69. 2019
- An Ad/MVA vectored Theileria parva antigen induces schizont-specific CD8+ central memory T cells and confers partial protection against a lethal challenge.. NPJ VACCINES. 3:35. 2018
- Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro.. Veterinary Immunology and Immunopathology. 199:8-14. 2018
- Characterization of the Theileria parva sporozoite proteome. International Journal for Parasitology. 48:265-273. 2018
- Immune parameters to p67C antigen adjuvanted with ISA206VG correlate with protection against East Coast fever. Vaccine. 36:1389-1397. 2018
- Effect of recombinant glutathione S-transferase as vaccine antigen against Rhipicephalus appendiculatus and Rhipicephalus sanguineus infestation. Vaccine. 35:6649-6656. 2017
- Preliminary efficacy investigations of oral fipronil against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions. Acta Tropica. 176:126-133. 2017
- Use of a novel antigen expressing system to study the Salmonella enterica serovar Typhi protein recognition by T cells.. PLOS Neglected Tropical Diseases. 11. 2017
- Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions. Malaria Journal. 15:324-324. 2016
- Genomic insights into the Ixodes scapularis tick vector of Lyme disease. Nature Communications. 7:10507-10507. 2016
- Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever. Scientific Reports. 6:20617-20617. 2016
- Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance. Molecular Microbiology. 99:55-70. 2016
- BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva.. Veterinary Immunology and Immunopathology. 167:80-85. 2015
- A method to discriminate between closely related bovine major histocompatibility complex class I alleles by combining established PCR‐SSP assays with RFLPs. Tissue Antigens. 85:278-282. 2015
- Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery. Immunogenetics. 66:705-718. 2014
- Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle. Veterinary Research. 45:50-50. 2014
- East Coast fever?Outlook for a new vaccine 2014
- Report from an ILRI strategy workshop on tick research, Cape Town, 24 August 2014 2014
- The ovarian transcriptome of the cattle tick, Rhipicephalus (Boophilus) microplus, feeding upon a bovine host infected with Babesia bovis. Parasites & Vectors. 6:276-276. 2013
- Gut transcriptome of replete adult female cattle ticks, Rhipicephalus (Boophilus) microplus, feeding upon a Babesia bovis-infected bovine host.. Parasitology Research. 112:3075-3090. 2013
- African Swine Fever (ASF) control: An entry point for enhancing human welfare through pig system improvement 2013
- Biosciences research at the International Livestock Research Institute (ILRI) 2013
- Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development 2013
- The quest for the needle (antigen) in the haystack (pathogen): Immunoinformatics to the rescue 2013
- Comparative genomic analysis and phylogenetic position of Theileria equi. BMC Genomics. 13:603-603. 2012
- Comparative Genome Analysis of Three Eukaryotic Parasites with Differing Abilities To Transform Leukocytes Reveals Key Mediators of Theileria-Induced Leukocyte Transformation. Mbio. 3. 2012
- Analysis of Babesia bovis infection-induced gene expression changes in larvae from the cattle tick, Rhipicephalus (Boophilus) microplus. Parasites & Vectors. 5:162-162. 2012
- Designing bovine T cell vaccines via reverse immunology.. Ticks and Tick-borne Diseases. 3:188-192. 2012
- A Rickettsia Genome Overrun by Mobile Genetic Elements Provides Insight into the Acquisition of Genes Characteristic of an Obligate Intracellular Lifestyle. Journal of Bacteriology. 194:376-394. 2012
- A schizont-derived protein, TpSCOP, is involved in the activation of NF-κB in Theileria parva-infected lymphocytes.. Molecular and Biochemical Parasitology. 174:8-17. 2010
- A Babesia bovis gene syntenic to Theileria parva p67 is expressed in blood and tick stage parasites.. Veterinary Parasitology. 173:211-218. 2010
- Sequencing of Culex quinquefasciatus Establishes a Platform for Mosquito Comparative Genomics. Science. 330:86-88. 2010
- Reassociation kinetics-based approach for partial genome sequencing of the cattle tick, Rhipicephalus (Boophilus) microplus. BMC Genomics. 11:374-374. 2010
- Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni.. Molecular and Biochemical Parasitology. 169:27-39. 2010
- Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8⁺ T cell responses. Veterinary Immunology and Immunopathology. 130:107-113. 2009
- Expression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family.. PLOS ONE. 4. 2009
- Genome Mapping and Genomics in Animal-Associated Microbes 2009
- Tick genomics?coming of age 2009
- A novel SINE family occurs frequently in both genomic DNA and transcribed sequences in ixodid ticks of the arthropod sub-phylum Chelicerata.. Gene. 415:13-22. 2008
- Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva.. Veterinary Immunology and Immunopathology. 115:383-389. 2007
- Approaches to improved understanding of vector parasite interaction within the genus Theileria and their Ixodid tick vectors 2007
- Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 103:3286-3291. 2006
- Vaccines against Theileria parva.. Annals of the New York Academy of Sciences. 916:464-473. 2006
- Using the transcriptome to annotate the genome revisited: application of massively parallel signature sequencing (MPSS).. Gene. 366:104-108. 2006
- Identification of candidate sialome components expressed in ixodid tick salivary glands using secretion signal complementation in mammalian cells.. Insect Molecular Biology. 14:403-414. 2005
- Genome of the host-cell transforming parasite Theileria annulata compared with T. parva.. Science. 309:131-133. 2005
- Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes.. Science. 309:134-137. 2005
- Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge. Vaccine. 23:3084-3095. 2005
- Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage. Nucleic Acids Research. 33:5503-5511. 2005
- Genes transcribed in the salivary glands of female Rhipicephalus appendiculatus ticks infected with Theileria parva. Insect Biochemistry and Molecular Biology. 34:1117-1128. 2004
- Improved immunogenicity of novel baculovirus-derived Theileria parva p67 subunit antigens. Veterinary Parasitology. 121:53-64. 2004
- Baculovirus surface display of Theileria parva p67 antigen preserves the conformation of sporozoite-neutralizing epitopes. PROTEIN ENGINEERING. 16:73-78. 2003
- AvGI, an index of genes transcribed in the salivary glands of the ixodid tick Amblyomma variegatum. International Journal for Parasitology. 32:1447-1456. 2002
- Functional expression of a bovine major histocompatibility complex class I gene in transgenic mice. Veterinary Immunology and Immunopathology. 87:417-421. 2002
- A cement protein of the tick Rhipicephalus appendiculatus, located in the secretory e cell granules of the type III salivary gland acini, induces strong antibody responses in cattle.. International Journal for Parasitology. 32:833-842. 2002
- Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells.. Parasitology. 125:497-505. 2002
- Molecular and immunological characterisation of Theileria parva stocks which are components of the 'Muguga cocktail' used for vaccination against East Coast fever in cattle.. Veterinary Parasitology. 94:227-237. 2001
- A 32 kDa surface antigen of Theileria parva : characterization and immunization studies. Parasitology. 120:553-564. 2000
- Cloning, Characterization, and Expression of a 200-Kilodalton Diagnostic Antigen of Babesia bigemina. Journal of Clinical Microbiology. 38:2240-2247. 2000
- Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva.. Parasite Immunology. 22:223-230. 2000
- Molecular characterisation of a Theileria lestoquardi gene encoding a candidate sporozoite vaccine antigen.. Molecular and Biochemical Parasitology. 107:309-314. 2000
- Theileria parva genomics reveals an atypical apicomplexan genome. International Journal for Parasitology. 30:465-474. 2000
- Cloning, sequence and mRNA expression of bovine interleukin-16.. Dna Sequence. 10:425-428. 2000
- Evaluation of recombinant sporozoite antigen SPAG-1 as a vaccine candidate against Theileria annulata by the use of different delivery systems.. Tropical Medicine & International Health. 4:A71-A77. 1999
- Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralizing epitopes: implications for a vaccine.. Infection and Immunity. 67:1261-1266. 1999
- Development of sero-diagnostic and molecular tools for the control of important tick-borne pathogens of cattle in Africa 1999
- Telomeric features of Theileria parva mitochondrial DNA derived from cycle sequence data of total genomic DNA. Molecular and Biochemical Parasitology. 95:159-163. 1998
- Conservation of Neutralizing Determinants between the Sporozoite Surface Antigens of Theileria annulata and Theileria parva. Experimental Parasitology. 82:229-241. 1996
- Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle 1995
- Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parva 1995
- A 7.1 Kb linear DNA molecule of Theileria parva has scrambled rDNA sequences and open reading frames for mitochondrially encoded proteins 1994
- Detection of a carrier state in Theileria parva-infected cattle by the polymerase chain reaction 1992
- Characterization of a repetitive DNA probe for Babesia bigemina 1990
- Bovine theileriosis. Progress in immunization methods 1980
document
review
- Contagious Bovine and Caprine Pleuropneumonia: a research community's recommendations for the development of better vaccines.. NPJ VACCINES. 66. 2020
- Approaches to vaccination against Theileria parva and Theileria annulata.. Parasite Immunology. 724-734. 2016
- The biology of Theileria parva and control of East Coast fever - Current status and future trends.. Ticks and Tick-borne Diseases. 549-564. 2016
- Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks. Parasitology. S271-S283. 2004
- Organisation and informational content of the Theileria parva genome. Molecular and Biochemical Parasitology. 1-8. 1998
- Prospects for subunit vaccines against tick-borne diseases.. British Veterinary Journal. 621-639. 1996